Christophe Michon

Chargé de recherches CNRS

Catalyse et Chimie Moléculaire


Bâtiment : C7

Bureau : 102

Téléphone : (+33) 03 20 43 68 63

Fax : (+33) 03 20 43 65 85

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Adresse :

Unité de Catalyse et Chimie du Solide - UMR CNRS 8181
ENSCL, Bâtiment C7
B.P. 90108
Université des Sciences et Technologies de Lille
59652 Villeneuve d’Ascq Cedex

Activités de recherche :

My research combines organic and organometallic chemistry for the development of new catalysts (organometallic as well as organic) and the synthesis of fine chemicals. Focus is on reactions like allylic alkylation, oxidation, hydrosilylation, aza-Michael and hydroamination. Reaction mechanisms are studied through the use of various means (NMR, IR, mass spectrometry, X-ray diffraction analysis…) performing control experiments and kinetics or by characterization of intermediates.

Parcours :

2014 : Habilitation (Habilitation à Diriger les Recherches) “Organometallic and organic chemistry for racemic and asymmetric homogeneous catalysis”.

2009-present : Chargé de recherche CNRS à l’UCCS depuis octobre 2009.

2008-2009 : ATER (100%, 12 months) Université Lille1 – UCCS- Dr. Francine Agbossou.

2007-2008 : Postdoc research associate (14 months), University of Geneva (Switzerland), Professor Jérome Lacour.

2005-2007 : Postdoc research associate (19 months), Kyoto Pharmaceutical University (Japan), Professor Motokazu Uemura.

2003-2005 : Postdoc research associate (21 months), Ames Laboratory-US Department of Energy at Iowa State University (USA), Professor Robert J. Angelici.

2000-2003 : PhD, guided by Dr. Jean-Pierre Djukic and Dr. Michel Pfeffer, Université Louis Pasteur, Strasbourg (France).

Publications récentes :

Dans la base de données : 29
  • 2017

  • Total Synthesis of (–)-Herbaric Acid through Organocatalyzed Asymmetric Halolactonization of Acrylate-Type Benzoic Acids.
    Deniau Eric, Michon Christophe, Gelat Fabien, Lebrun Stéphane, Henry Natacha, Agbossou-Niedercorn Francine.
    Synlett, vol. 28, pg. 225-230 (2017) DOI
  • Efficient and Selective Hydrosilylation of Secondary and Tertiary Amides Catalyzed by an Iridium(III) Metallacycle: Development and Mechanistic Investigation.
    Corre Yann, Trivelli Xavier, Capet Frédéric, Djukic Jean-Pierre, Agbossou-Niedercorn Francine, Michon Christophe.
    ChemCatChem, vol. 9, pg. 2009-2017 (2017) DOI
  • 2016

  • Pentamethylcyclopentadienyl Iridium(III) Metallacycles Applied to Homogeneous Catalysis for Fine Chemical Synthesis.
    Michon Christophe, MacIntyre Kirsty, Corre Yann, Agbossou-Niedercorn Francine.
    ChemCatChem, vol. 8, pg. 1755-1762 (2016) DOI
  • Regioselective hydrosilylation of terminal alkynes using pentamethylcyclopentadienyl iridium(III) metallacycle catalysts.
    Corre Yann, Werlé Christophe, Brelot-Karmazin Lydia, Djukic Jean-Pierre, Agbossou-Niedercorn Francine, Michon Christophe.
    Journal of Molecular Catalysis A: Chemical, vol. 423, pg. 256-263 (2016) DOI
  • Regioselective organocatalyzed asymmetric bromolactonization of aryl acrylate-type carboxylic acids: a new approach towards enantioenriched 3-substituted isobenzofuranones.
    Gelat Fabien, Coffinet Michaël, Lebrun Stéphane, Agbossou-Niedercorn Francine, Michon Christophe, Deniau Eric.
    Tetrahedron: Asymmetry, vol. 27, pg. 980-989 (2016) DOI
  • Selective Hydrosilylation of Esters to Aldehydes Catalysed by Iridium(III) Metallacycles through Trapping of Transient Silyl Cations.
    Corre Yann, Rysak Vincent, Capet Frédéric, Djukic Jean-Pierre, Agbossou-Niedercorn Francine, Michon Christophe.
    Chemistry - A European Journal, vol. 22, pg. 14036-14041 (2016) DOI
  • Synthesis of symmetrical diaryl ketones by cobalt-catalysed reaction of arylzinc reagents with ethyl chloroformate.
    Rérat A, Michon C, Agbossou-Niedercorn F, Gosmini C.
    Eur. J. Org. Chem., vol. 2016, pg. 4554-4560 (2016) DOI
  • 2015

  • Efficient hydrosilylation of imines using catalysts based on iridium(iii) metallacycles.
    Corre Y., Iali W., Hamdaoui M., Trivelli X., Djukic J.-P., Agbossou-Niedercorn F., Michon C.
    Catal. Sci. Technol., (2015) DOI
  • Chiral Phase-Transfer-Catalyzed Intramolecular aza-Michael Reactions for the Asymmetric Synthesis of Isoindolinones.
    Lebrun Stéphane, Sallio Romain, Dubois Mélanie, Agbossou-Niedercorn Francine, Deniau Eric, Michon Christophe.
    European Journal of Organic Chemistry, vol. 2015, pg. 1995-2004 (2015) DOI
  • 2014

  • Mononuclear gold catalysts for the asymmetric intramolecular hydroamination of alkenes.
    Michon Christophe, Abadie Marc-Antoine, Medina Florian, Agbossou-Niedercorn Francine.
    Catalysis Today, vol. 235, pg. 2-13 (2014) DOI
  • Asymmetric Intramolecular Hydroamination of Alkenes in Mild and Wet Conditions-Structure and Reactivity of Cationic Binuclear Gold(I) Catalysts.
    Abadie Marc-Antoine, Trivelli Xavier, Medina Florian, Capet Frédéric, Roussel Pascal, Agbossou-Niedercorn Francine, Michon Christophe.
    ChemCatChem, vol. 6, pg. 2235-2239 (2014) DOI
  • Molybdenum(VI) dioxo complexes for the epoxidation of allylic alcohols and olefins.
    Pandhare Swati L., Jadhao Rajesh R., Puranik Vedavati G., Joshi Pranaya V., Capet Frédéric, Dongare Mohan K., Umbarkar Shubhangi B., Michon Christophe, Agbossou-Niedercorn Francine.
    Journal of Organometallic Chemistry, vol. 772-773, pg. 271-279 (2014) DOI
  • Efficient gold(I) catalysed asymmetric hydroamination of alkenes.
    Abadie M -A, Medina F, Agbossou-Niedercorn F, Michon C.
    Chimica OGGI – Chemistry Today , vol. 32 (6), pg. 19-21 (2014)
  • 2013

  • Catalytic Asymmetric Allylic Alkylation of 3-Arylated Piperidin-2-ones.
    Michon Christophe, Béthegnies Aurélien, Capet Frédéric, Roussel Pascal, de Filippis Arnault, Gomez-Pardo Domingo, Cossy Janine, Agbossou-Niedercorn Francine.
    European Journal of Organic Chemistry, vol. 22, pg. 4979-4985 (2013) DOI
  • Enantioenriched Isoindolinones from Chiral Phase-Transfer-Catalyzed Intramolecular Aza-Michael Reactions.
    Michon Christophe, Deniau Eric, Sallio Romain, Lebrun Stéphane, Schifano-Faux Nadège, Goossens Jean-François, Agbossou-Niedercorn Francine.
    Synlett, vol. 24, pg. 1785-1790 (2013) DOI
  • Uncatalysed intermolecular aza-Michael reactions.
    Medina Florian, Duhal Nathalie, Michon Christophe, Agbossou-Niedercorn Francine.
    Comptes Rendus Chimie, vol. 16, pg. 311-317 (2013) DOI
  • Preparation of chiral key intermediates of morpholine based neurokinin receptor antagonists by asymmetric allylic alkylation.
    Keldenich Jérôme, Denicourt-Nowicki Audrey, Michon Christophe, Agbossou-Niedercorn Francine.
    Tetrahedron, vol. 69, pg. 6424-6430 (2013) DOI
  • Asymmetric Intramolecular Hydroamination of Allenes using Mononuclear Gold Catalysts.
    Michon Christophe, Medina Florian, Abadie Marc-Antoine, Agbossou-Niedercorn Francine.
    Organometallics, vol. 32, pg. 5589-5600 (2013) DOI
  • 2012

  • Alternative strategies for the stereoselective synthesis of enantioenriched 6-arylated piperidin-2-ones.
    Sallio Romain, Lebrun Stéphane, Agbossou-Niedercorn Francine, Michon Christophe, Deniau Eric.
    Tetrahedron: Asymmetry, vol. 23, pg. 998-1004 (2012) DOI
  • Intermolecular Mono- and Dihydroamination of Activated Alkenes Using a Recoverable Gold Catalyst.
    Medina Florian, Michon Christophe, Agbossou-Niedercorn Francine.
    European Journal of Organic Chemistry, vol. 2012, pg. 6218-6227 (2012) DOI
  • 2011

  • Adventitious formation of a new oxopentadienyl Mn(I) tricarbonyl complex: Structural study and bonding investigation of (η5-CH2C(Fc)CHC(Fc)O)Mn(CO)3.
    Djukic Jean-Pierre, Michon Christophe, Pfeffer Michel, Gruber-Kyritsakas Nathalie, de Cian André.
    Journal of Organometallic Chemistry, vol. 696, pg. 3268-3273 (2011) DOI
  • Synthesis of a Chiral Key Intermediate of Neurokinin Antagonist SSR 240600 by Asymmetric Allylic Alkylation.
    Agbossou-Niedercorn Francine, Keldenich Jérôme, Michon Christophe, Nowicki Audrey.
    Synlett, vol. 2011, pg. 2939-2942 (2011) DOI
  • 2010

  • Inter- and Intramolecular Hydroamination of Unactivated Alkenes Catalysed by a Combination of Copper and Silver Salts: The Unveiling of a Brønstedt Acid Catalysis.
    Michon Christophe, Medina Florian, Capet Frédéric, Roussel Pascal, Agbossou-Niedercorn Francine.
    Advanced Synthesis < Catalysis, vol. 352, pg. 3293-3305 (2010) DOI
  • Stereoselective synthesis of configurationally stable functionalized ethano-bridged Tröger bases.
    Michon Christophe, Sharma Ankit, Bernardinelli Gérard, Francotte Eric, Lacour Jérôme.
    Chemical Communications, vol. 46, pg. 2206 (2010) DOI
  • 2009

  • Solid-State NMR Investigations of the Immobilization of a BF4−Salt of a Palladium(II) Complex on Silica.
    Wiench Jerzy W., Michon Christophe, Ellern Arkady, Hazendonk Paul, Iuga Adriana, Angelici Robert J., Pruski Marek.
    Journal of the American Chemical Society, vol. 131, pg. 11801-11810 (2009) DOI
  • NMR enantiodifferentiation of quaternary ammonium salts of Tröger base.
    Michon Christophe, Gonçalves-Farbos Maria-Héléna, Lacour Jérôme.
    Chirality, vol. 21, pg. 809-817 (2009) DOI
  • Regiochemical observations depending on electrophiles in directed lithiation of 1,3-diheteroatom substituted arene tricarbonylchromium complexes.
    Michon Christophe, Murai Masato, Nakatsu Mai, Uenishi Jun' , Uemura Motokazu.
    Tetrahedron, vol. 65, pg. 752-756 (2009) DOI
  • 2008

  • Gold(I)-Catalyzed Cycloisomerization of (Arene)chromium Complexes with Enyne Bonds Directed Towards Axially Chiral Biaryls.
    Uemura Motokazu, Michon Christophe, Liu Suyun, Hiragushi Shinya, Uenishi Jun’ichi.
    Synlett, vol. 2008, pg. 1321-1324 (2008) DOI
  • Cycloisomerization of (arene)chromium complexes with enyne by gold(I) catalyst for axially chiral biaryls.
    Michon Christophe, Liu Suyun, Hiragushi Shinya, Uenishi Jun' , Uemura Motokazu.
    Tetrahedron, vol. 64, pg. 11756-11762 (2008) DOI